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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9ed44b12af6cc1c629aebfaa9119584990d344cb7d2be4eb1d5191f8cf2285d' 
  AND token = 'POIiQ4DV7KB5buQij/gH8TMzvfBBx+D4Vh0yk0noYK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}