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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b022b807ab0207d2139281a78b489a0a38724c1f4fb05da49e2bb213e9ff9f73' 
  AND token = 'Uah2J6OA38llLcdVj9+VUWDMbo7JZLSzhH1iPB1fUxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}