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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f7818ded7b5512f4ef47501920718d38dbd314b5c367792b38b5a2592923374' 
  AND token = '0PUOHla8Pcij0Yci0AOL0p4t6eY7FKeFNTvDfotxtQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}