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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c23f02a7700821ab58eb93182a594e7fcda30d83140ba958b9835ab7e1e8686f' 
  AND token = 'd/EFYXgHETEU2h4hykQnSC7VkwEii89E04Cst5GvEBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}