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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7900aa2614227d2c96c930a4bf3888d87c81562e0df2b7d8b8d2e11020c71eb' 
  AND token = 'jAcbJn5i49+G9+XBs8mTTTLxgQm7oj7S7xUvZKr+KTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}