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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2529685e1526007c8ab6a7ff254fe99058b8fa4fcbdc0b1b0715b921ff076658' 
  AND token = '6v+Idc0CjxibYTCKOfHsmo0UPV4lr84KwaZ2xrdLzto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}