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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae3c41e30e2ef4db0f9530a38f230186fcaee89bc1405a989d10e62dee55d03b' 
  AND token = 'GsRu6YXi9AiGgnxFoBxuN1QRhtVLTaDbZ5688PtVWDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}