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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6412bc2c67d676c0792956c973a924d99fb08fda3241818b31fdb33308a081f1' 
  AND token = 'fsJDdkSeQ8MzT4TL7dGN7+Dof9x9kYgyPesyJ4Qk11Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}