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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c136db40cbcfe7f735f2807e708627ed1e440882ec672aec060487715aa488c' 
  AND token = 'jPuTDwLT5Jm9A3dUOybykvAwfF0HMzfGHOloRK1xpoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}