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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949e059c3be28aa1c17b25ecb09c8702b4c0c5e5e699826677cd17008faeeda3' 
  AND token = 'Y/LM7/w3zB0n8cuWxNw6XoiBoah0vvi7eVB4RjdUhNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}