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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb5df03878a327e5ac9dcb98bdd7bb3e018ab92f7a60d642f568666516f7ebf6' 
  AND token = 'PmGtcCh9Zt1Vx8W+VvxXfg0E39AWNJN7BflZflUZ+d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}