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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c1a5a16293945544d9d99bb2daba65fd489e30a455f8442acaf969c4b8244a' 
  AND token = 'PBk9VpHxe+r+zeVYteM5i0Grp7QAfqasTK4t5TQQcLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}