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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da0750691051e54ee6ac2260a106a3998f8f0c231142ed143a9ecbfb236d4155' 
  AND token = 'bPDalBDFMyzhmbuNJt6EN2eEwOQZYF7hMf9Crh6zjFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}