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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ce78a6badf4a72f704a5a28918119a98950aedf5454eea7759b6856ea3366c' 
  AND token = 'CK8rdYC9BkYTgVF54AfuiFB59CWCqiHH3cWWwSwBcb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}