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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6e0f546bc1bf5e00ba92f809d7cce396c0fc21b843a1ee92b253b926553220' 
  AND token = 'shBrKRq0pL84gg+v5HC89fbdeA/7+odHUV5IKeChDls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}