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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '210c5104ad9321594dbd278128c209418f71c79d60673aea1e5c305bb7e7f286' 
  AND token = 'hmfKGn0ZotW2ca98lrhjui75C4mMWYJL6TF1e0WesEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}