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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722bd9d547576aa007f0e47966079993bc16041d2364e1c164119282a67df30a' 
  AND token = '6MYp+yQ7ttJciPWjih5vC6ipuYL10bGDr5Q3YfWMpDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}