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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12de7e13e210ecb0c62840942203d64d6ca1cb3ee77dfabcbed7eefc9229301' 
  AND token = 'dREGrSu9bKStkIqWsabFkfcL8BUeBXJ1Odemh09Z6DU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}