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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4672188fa26e70887a4eaa60b1c1f6c80b5ea59329ad8e3932d2bbc89dd43b46' 
  AND token = 'fBYbAMj9l8wk2qhSRe9/3+dEWOgx7lxb6VayGgMgIzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}