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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8b7f1468e4197e0ba803b65336301aa5b02c30c21170aca778e9607a6e43c4' 
  AND token = 'w1EywDv0Qy3/l27M1GkP1UU908ZANai141SVdX/nkqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}