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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d377f9985ae199b5bf25c5f62669c8f8db44d6e66f06d6c3b2ed0d6ddf6a3c0' 
  AND token = 'mYuONyERjpRhzQgnado6DnxVr/fM60aOMvBbW3ep0kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}