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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ad1c6c1af47b924b306195557249e754597bb6384764ea88a5bcef5174ac78' 
  AND token = 'yX4zoKgrGYb3kv/NSGl+UbSl1P26YAUNYFMHMnmsY+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}