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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27b12aa635feff1d261bcfdca45b1b8862942ec995bfbedf5bd3632dbe36a8af' 
  AND token = 'hCgtHMWU+hCTKqvnq/R7OlH32S4k2M67dJZX4cN0mRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}