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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85e2616cf29e5261ab2f79e958deab19c846443cb378742f463513d4f60ecaf6' 
  AND token = '4rLYlvFRreP+oFE6utTLV6u9n07iVx73uiKos5j4aFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}