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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22b4b248e54d9f6c09fa094e7daa76b05187523795a9fdc88bb5c09a71aa27f' 
  AND token = 'ecxyki5CE5PfB/bzsStVQkmwQGXf3y550GtoOlwK2po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}