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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6087c0f17eaf95f98a1b051069f4933b9b68f3d1650019a9a97cb44b1365102' 
  AND token = '+/ntEMaW3tYOUHMxWYezhD84ibCIH9yYMrxLPGNLcDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}