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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a51ad60ce5304e3dd3df07b64f08a770084c0eb7a42b08ca4a868d6445d68f0' 
  AND token = 'oxAeKDafJ2HgfGA5UQ/PBHJ8rwHaArU4NDRqfR1uObg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}