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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de210ed45d67cb78ba7f8b731f17bad3481a9f621ac4ea97a8f167fec28c4468' 
  AND token = 'D8uNxlPdHXrWpBVCpLM2x/4ATO21FgSZ9w3dOEy3uIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}