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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12e648ba6f1b64ec4a02435124e1a82533f843206bfe5245c306e4adf67a49a2' 
  AND token = 'zzuk6N9/8xyCnV+5QAbkbsW9ZUkTmm2+PyctG5/PFYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}