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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e497c13197b877281ef91cc0ae1c56114e587d79281d6cac9a0af82249d4285' 
  AND token = '7zIcr/R3iMDrWSy5w3mqVuO2gKpDecG7/zJL7vg3MYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}