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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '424ec4b27c6d9b0a924f5eae7b7d711cb31bbd59a74c03ac24fa3443c9102c82' 
  AND token = 'HBU5yvjN3QYhydAku7baWcAwFN5VvBDlkmJxKxih6Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}