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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1903e576a496139ba296d08510e2840fb51216bfb3691a37e3614c57945498db' 
  AND token = 'dHM05upmzhPtz8Vzz1/fHc9Da770b5nSFoIlYvmAVTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}