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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ace14c13e73eca0ba71f710a834fdf436a49f2b00d87daed50b773b34abd714' 
  AND token = '9FAzjnLybGHXjWsfUKRblYDpf3o+0BM6xdbSxwe4wDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}