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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b22f06aed0fab5ecdfc4936de433a247d3adbe0f31054977b84c20d56ebc573' 
  AND token = 'KpntiQ0qYQ14ux5lGXIi5iFjX+pnl0NmsnVlyvKDYcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}