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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12230a28abf74db4bd28e570d318cb812155b309fa45d3a1c2ab65a22eebc0f3' 
  AND token = 'DXvrCLvPnxM0EPmrwh1d/Q/uT4p2R5xqk/cb1g+SFLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}