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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ee41d7bb8fc0e0c2371acee210d84212c5c9b53a8e490544407e2e9037c8448' 
  AND token = 'YUWyyRWB11e7ocelWWqfRoDN/NgXaP146avskQhLU4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}