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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66eda5660348e32b8832fa1bead9425fe226b1e06907dbd39c11aab84e157dd' 
  AND token = 'M2TfF+JTrvIGUqC/7PTDoGQNFMbEY6NZuMWdt/oLw9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}