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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bf623a0dd3bcb5060ae97f186b7df042828b4971da78c9f7f3602daa20d1ecf' 
  AND token = 'fuReyVOIUFy5IMNG1Z9MbHXgrhyDm0L8xoW6cqlxH8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}