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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5df8b8ad0c784d6afd000c0ab959adb5d25e3f215b2d0b493da271799363909' 
  AND token = 'WCwFZzDUdbuGtxhDfXQbFzT65YNdRwzZdCgICWAZ0lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}