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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cf982dd36a51f970880e980a9082ebf015f8b336ae7be85fccc77fb013be00' 
  AND token = 'Gc4A3XP5pop1JvMBK2xMVMnc5X/lIdc4Gdse9ANxfKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}