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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5c4a0f8810210c7b478b6a27429fd1370a59f97a5811d9fd21b0c6a5497f61' 
  AND token = 'gDbkAxfpDioW7BhKKnj6pNmLWT1LB3i0F0ufX8+yYhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}