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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb95b061f8f7c0729ab7f960c89398c151410b42bc1a937b3ca5a48f4a5478c6' 
  AND token = 'JKT6ohFAcxc0HWOprx0jr0c357lSobS8RzdGTFEfttE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}