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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8539b34bdffc041d62f6feaa5f02aa12ccfc3b365b0463a8acf14e05feec66b8' 
  AND token = 'Qg/HRkjAj/NJ8gvtVRkpHbSS0iFF9zIVz07ngC1VdhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}