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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e90f75277e4e27309af101c63c74f66cbfc9e642e0f24ad47192ee8094520b8' 
  AND token = '8lVSadPdS2HpOTtDT9dVW67msOZTpnFAY8s2P8E87Ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}