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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea05b9188a3f44cca9009b18541c48608ba50e8b520466db63c561c93a560fb7' 
  AND token = '4XtuxpxMxPF2Gxgf+9raiLAoPOW6T0kkBCHmgunaN40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}