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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a25c9957fde965c9e741fcc8375b203548e6790d8ee0f5dbc9b6f380bbfc1fcd' 
  AND token = 'i54rcGKSKiFbP99o7pbuRTIOVnTUEIJx3EghRpiUWh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}