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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44a145410a2ab5d20a5412fcff97810e0aaa0dd1ef8e84ee5a03c29bb439011a' 
  AND token = '+pSMbdbU/h5uRaiQUoBFSEMCMNJZT5OlNEB6OuCRIMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}