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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bee0a3595b94c398ba85f069b6395f30902f43459dc1dde3732fab8b30c5ec1' 
  AND token = 'NhkwdBVgQjWQSo0biUX8OmJcNn8lO7IPsyXcH/gcU1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}