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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2abe22f04ca7e90ef57aaa879eb1aecb28285059055d3ba5b53c9af363f0bb2d' 
  AND token = 'aQKvOGbBn31PKuwOHfQIJ2cJl+i+awI+XRx8Hvp+XzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}