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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4552cf27bfe8344672afaf563d70f675d66dd1f3494eff8cb982973a1ff12566' 
  AND token = '3IZUpVk3m6ncNS3vZDuFDnB8BlYFcESg3xNlTAUEIZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}